I am involved with a discussion group on the NAMI website (National Alliance on Mental Illness). Someone from the group posted a website with Stanford’s Dr. Sapolsky giving a 52-minute lecture on depression that is one of the most complete and integrated descriptions of depression that I’ve ever seen from the body and soul sides (he does not bring in the spirit). He posits that depression is as real of a biological disease as diabetes…and also covers the components of psychological, stress, genetics, hormones, medical conditions, and more that have an impact on depression. Knowledge leads to understanding and understanding leads to healing. Here is the link to the lecture: http://www.youtube.com/watch?v=NOAgplgTxfc. I highly recommend you take it in.