When a person remains in a depressed condition, even after normal efforts to remedy the condition, a physical source of depression should be considered, especially in the case of debilitating or suicidal depression.
Physiological causes of depression are relatively common. For example, any person with ongoing depression should be checked for hypothyroidism. Other physical sources of depression include:
- Nutritional deficiencies
- Hormonal disorders
- Food allergies
- Heavy metals (mercury, lead, aluminum, etc.)
- Selenium toxicity
- Sleep disturbances
- Dental problems
- Infections of various types
- Medical conditions, including heart and lung problems, diabetes, chronic pain, chronic inflammation, and many others.
- Drugs such as high blood pressure medications, anti-inflammatory agents, corticosteroids, cycloserine (an antibiotic), and many others.
- Low testosterone in men; premenstrual syndrome in women
This information came from http://alternativementalhealth.com/articles/depression.htm, and you can receive much more information by going to that site. Some of these I knew of; others were new to me. As with any information on-line, do additional research to determine if the information you are reading is valid. You could also talk to a doctor who understands depression and the physical causes of it. That may not be your family doctor.